Archive for February, 2010

An HDAC inhibitor increases AcMNPV gene expression in mammalian cells

February 28th, 2010

Abstract  The baculovirus Autographa californica multiple nucleopolyhedrovirus (AcMNPV) is used as a safer viral vector in mammalian cells with potential applications in gene therapy. However, the mechanism
for the insusceptibility of mammalian cells to proliferative infection by entomopathogenic viruses is not well understood.
Here, we studied the significance of epigenetic modifications such as histone acetylation, histone methylation and HP1 accumulation
for AcMNPV gene expression in mammalian BHK cells. Real-time PCR and chromatin immunoprecipitation with sodium butyrate revealed
an important relationship between viral gene expression and histone acetylation, with implications for a mechanism of suppression
of AcMNPV gene expression in BHK cells.

Content Type Journa…

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Sap’s rising: Maple syrup hobbyists head for woods to boil down syrup and make sweet money

February 28th, 2010

Sap’s rising: Sweet money for maple syrup hobby

IRA, Vt. — Eric May wasn’t too keen on the taste of real maple syrup when he first moved to Vermont but he tapped some trees anyway, borrowing buckets from neighboring farmers. After boiling the sap for 18 hours in a pot over an outside fire, he produced …. Original article  : Sap’s rising: Maple syrup hobbyists head for woods to boil down syrup and make sweet money.

Iran’s supreme leader: Nuclear watchdog under US influence; denies making nuclear bombs

February 28th, 2010

Iran: US behind IAEA charge that Iran making bomb

TEHRAN, Iran — Iran’s supreme leader charged Sunday that U.S. and its allies are behind the U.N. nuclear watchdog agency’s claim that Iran may be making nuclear bombs, despite its repeated denials.
The comments by Ayatollah Ali Khamenei, broadcast on state television Sunday, came 10 days after the …. Source  : Gaea News Network.

Salesforce Recently Rolled Out Salesforce Chatte, Social Networking for Enterprises

February 28th, 2010

 A few days back, Salesforce.com, the famous cloud computing company , announced  the Beta program of Social Neworking tool for Enterprises, Social Chatter. The software will be available during the calendar year of 2010. Customers will be able to access Chatter’s real time feed anytime  and anyplace through iPhone or Blackberry. Companies are having a hard … Read this article on Gaea Times at : Salesforce Recently Rolled Out Salesforce Chatte, Social Networking for Enterprises.

US troops allowed access to Twitter and Facebook

February 28th, 2010

LONDON – US troops are to be allowed to use social networking websites such as Twitter and Facebook following a review of internet use and security.

The BBC quotes defence department officials as saying that the benefits of using social media now …. Original source  : US troops allowed access to Twitter and Facebook.

The New iPhone App, TigerText can Help Cheating Spouses

February 28th, 2010

  Using TigerText, user can set a time limit about the text message to stay after it is read. When the limit exceeded, the message will disappear from the recipient’s phone, the sender’s phone and any servers. After this, you can not forward the message to anywhere, store the message or sold it to a flashy [..] Read the original article: here.

CSC news roundup 2010-02-28

February 28th, 2010

How to Install and Configure DKIM On Postfix With dkim-milter (2.8.x) on 64 bit CentOS 5

February 28th, 2010

The following document was written after countless hours of research and experimentation, in the hope that you will not have to waste as much time in setting up DKIM on Postfix as we had to. The documents in internet on this subject are mostly old and deals with an old version of DKIM Milter.

What is …. Source  : How to Install and Configure DKIM On Postfix With dkim-milter (2.8.x) on 64 bit CentOS 5.

Academy ponders action against ‘Locker’ producer who sent e-mails soliciting Oscar votes

February 28th, 2010

‘Lockergate’?: Producer apologizes for e-mails

LOS ANGELES — The Academy of Motion Picture Arts and Sciences is considering action against a producer of “The Hurt Locker” who sent out multiple e-mails urging academy members to vote for his movie in the Oscar best-picture category and “not a $500 million film,” an obvious reference to close-competitor “Avatar.”
The … Read more >>.

How to use iPhone for Controlling Household Electronic devices

February 28th, 2010

more images
iPhone is fast gaining the status of all-purpose gadget with bags of apps for almost everything. One of its most enticing functions include the ability to double up as a remote control for limited features on your iTunes’.  However, the developers have decided to break it out of the conventional usage. It might be …. Source article on Gaea Times at  : How to use iPhone for Controlling Household Electronic devices.

Woman shares abortion experience live on Twitter, YouTube

February 28th, 2010

NEW YORK – A woman took to her Twitter page to tell all about the abortion she was going through – step by step.

Angie Jackson, 27, wanted to “demystify” abortion, and so shared it on Twitter, YouTube and her personal blog.
“I’m doing this so other women know, ‘Hey, it’s not nearly … Read this article on Gaea Times at : Woman shares abortion experience live on Twitter, YouTube.

Ed Miliband becomes latest victim of ‘Twitterjacking’ scam

February 28th, 2010

LONDON – British Labour politician Ed Miliband has become the latest victim to have his Twitter account hacked by wrongdoers who are bent on embarrassing politicians.

The ‘Twitterjacking’ scam has caught out a series of politicians including the Leader of the House of Commons, Harriet Harman.
It was supposed to be …. Source article on Gaea Times at  : Ed Miliband becomes latest victim of ‘Twitterjacking’ scam.

National Conference demands apology from Opposition for Facebook slur

February 28th, 2010

Jammu, Feb 27 (ANI): The ruling National Conference has demanded an apology from the state’s main opposition People’s Democratic Party (PDP) for depicting three generations of the Abdullah family as ‘3 Idiots’ on social networking site Facebook.

Finance Minister Abdul Rahim Rather slammed the PDP for ’stooping low … Read more »»».

Inhibition of Cell Proliferation of Tenon’s Capsule Fibroblast by S-Phase Kinase-Interacting Protein 2 Targeting SiRNA through Increasing p27 Protein Level [Glaucoma]

February 27th, 2010

Skp2 siRNA inhibited cell proliferation and decreased cell viability of rTF in vivo and in vitro. SiRNA-mediated gene silencing of Skp2 can be a novel gene therapy to treat scarring after glaucoma surgery by the suppression of p27kip1 downregulation. (Source: Investigative Ophthalmology)

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Enhanced anti-tumor effects of combined MDR1 RNA interference and human sodium/iodide symporter (NIS) radioiodine gene therapy using an adenoviral system in a colon cancer model

February 27th, 2010

Enhanced anti-tumor effects of combined MDR1 RNA interference and human sodium/iodide symporter (NIS) radioiodine gene therapy using an adenoviral system in a colon cancer model

Cancer Gene Therapy advance online publication, February 26, 2010. doi:10.1038/cgt.2010.3

Authors: S J Ahn, Y H Jeon, Y J Lee, Y L Lee, S-W Lee, B-C Ahn, J-H Ha
& J Lee (Source: Cancer Gene Therapy)

Effective immunotherapy of weakly immunogenic solid tumours using a combined immunogene therapy and regulatory T-cell inactivation

February 27th, 2010

Authors: M C Whelan, G Casey, M MacConmara, J A Lederer, D Soden, J K Collins, M Tangney
& G C O’Sullivan (Source: Cancer Gene Therapy)

Gene Mutation in Mice Sheds Light on Autism

February 27th, 2010

Drugs targeting obsessive behavior might hold promise for people

Source: HealthDay
Related MedlinePlus Pages: Autism, Genes and Gene Therapy (Source: MedlinePlus Health News)

A highly efficient short hairpin RNA potently down-regulates CCR5 expression in systemic lymphoid organs in the hu-BLT mouse model

February 27th, 2010

Inhibiting the expression of the HIV-1 coreceptor CCR5 holds great promise for controlling HIV-1 infection in patients. Here we report stable knockdown of human CCR5 by a short hairpin RNA (shRNA) in a humanized bone marrow/liver/thymus (BLT) mouse model. We delivered a potent shRNA against CCR5 into human fetal liver-derived CD34+ hematopoietic progenitor/stem cells (HPSCs) by lentiviral vector transduction. We transplanted vector-transduced HPSCs solidified with Matrigel and a thymus segment under the mouse kidney capsule. Vector-transduced autologous CD34+ cells were subsequently injected in the irradiated mouse, intended to create systemic reconstitution. CCR5 expression was down-regulated in human T cells and monocytes/macrophages in systemic lymphoid tissues, including gut-associated…

Hawaii newspaper deal may lead to Honolulu becoming single-newspaper town

February 27th, 2010

For sale: a newspaper in paradise
HONOLULU — Honolulu barely escaped becoming a one-newspaper town about a decade ago. Many believe the death of one its two dailies is inevitable this time around.

The parent company of the Honolulu Star-Bulletin announced Thursday it was purchasing longtime rival The Honolulu Advertiser, the largest newspaper in Hawaii, and would …. Source article  : Hawaii newspaper deal may lead to Honolulu becoming single-newspaper town.

Is the Latest Union Budget a Good or Bad News for Indian IT Industry?

February 27th, 2010

 Although, 2010-11 Union Budget has brought some good news for the construction, hospitality, banking, education and pharma sectors, but, it does not generate any good news for IT industry. The Finance minister didn’t mention anything about the extension of Tax Rebate in this budget for IT industries.

Since, the tax break ends in Mar 2011, outsourcing …. Original article  : Is the Latest Union Budget a Good or Bad News for Indian IT Industry?.







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